Type 1 Diabetes Risk Factors
Research scientists are still trying to identify the risk factors that lead to type 1 diabetes. Here are two possibilities.
Viral infection
Several studies suggest that type 1 diabetes may be triggered by a particular kind of viral infection that occurs during childhood or early adulthood or during a mother's pregnancy. Scientists think the virus may trigger changes in the child's immune system, perhaps by creating antibodies that are capable of attacking beta cells. When a similar viral infection occurs later in the child's life, it may reactivate these antibodies so they begin to destroy beta cells.
Heredity
Your family history plays a small role. If one of your parents or grandparents has type 1 diabetes&$151;especially your father or grandfather&$151;your risk of developing the disease is increased but only slightly. Most people with type 1 diabetes, however, have no family history of the disease. Yet research suggests that some genetic susceptibility to type 1 diabetes must be present for the disease to occur.
Physician-developed and -monitored.
Original Date of Publication: 20 Apr 2009
Written by: Christopher D. Saudek, M.D.; Simeon Margolis, M.D., Ph.D.
Last Reviewed: 05 May 2009
Diabetes (Diabetes Mellitus), Diabetes Risk Factors - Type 1 Diabetes reprinted with permission from
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